Southern Squash Casserole

Highlighted under: Comfort Food

Delight your taste buds with this creamy, cheesy Southern Squash Casserole that brings a comforting touch to any meal. Packed with fresh butternut squash, a blend of savory herbs, and topped with a crispy breadcrumb crust, this dish is perfect for potlucks or family dinners. Easy to make and loaded with flavor, it’s a must-try for butternut squash lovers!

Created by

Emma

Last updated on 2025-10-18T08:40:30.628Z

This Southern Squash Casserole is not just a side dish; it’s a celebration of flavors that captures the essence of Southern cooking. The combination of tender butternut squash and rich, cheesy goodness will have everyone coming back for seconds!

Perfect for All Occasions

Southern Squash Casserole is not only a delicious dish but also incredibly versatile. It's perfect for family dinners, holiday gatherings, or casual potlucks. The creamy texture and cheesy flavor make it a crowd-pleaser that appeals to both adults and kids alike. Plus, it’s a great way to incorporate seasonal produce into your meals, making it an ideal choice for both summer barbecues and winter feasts.

When served warm, this casserole acts as a comforting side dish that pairs beautifully with meats such as roasted chicken, grilled pork, or even vegetarian dishes. Its rich flavors complement a wide array of main courses, enhancing the overall dining experience with its savory, herbed profile.

Health Benefits of Butternut Squash

Butternut squash is packed with essential nutrients, making it a healthy addition to your diet. This seasonal squash is rich in vitamins A and C, providing antioxidants that promote eye health and boost your immune system. Additionally, butternut squash is a great source of dietary fiber, which aids digestion and helps maintain a healthy weight.

Incorporating butternut squash into your meals can also help improve skin health due to its high beta-carotene content. Plus, its naturally sweet flavor allows you to enjoy a nutritious dish without compromising on taste. This casserole is a delightful way to encourage vegetable consumption in a delicious and approachable manner.

Customization and Variations

One of the best aspects of Southern Squash Casserole is its adaptability. Feel free to experiment with different cheeses, such as Gruyère or Monterey Jack, to alter the flavor profile. You can also add vegetables like spinach, bell peppers, or zucchini for extra nutrition and texture, creating a unique twist for every occasion.

For those looking to reduce calories, consider using low-fat milk or a dairy-free alternative. Additionally, incorporating fresh herbs or spices can elevate the dish and give it a personal touch. With a bit of creativity, you can make this casserole your own while retaining its beloved comfort food essence.

Ingredients

Ingredients for Southern Squash Casserole

2 medium butternut squash, peeled and cubed
1 cup onion, chopped
1 cup cheddar cheese, shredded
1 cup milk
1/2 cup breadcrumbs
2 tablespoons butter, melted
2 teaspoons salt
1 teaspoon black pepper
1 teaspoon garlic powder
1 teaspoon dried basil

Combine all ingredients in a large mixing bowl before moving on to the next steps.

Instructions

Prepare the Squash

Bring a large pot of salted water to a boil. Add the cubed butternut squash and cook until tender, about 10-15 minutes. Drain and set aside.

Mix Ingredients

In a large bowl, combine the cooked butternut squash, chopped onion, cheddar cheese, milk, and spices. Mix well until everything is evenly combined.

Assemble the Casserole

Transfer the mixture into a greased baking dish. Sprinkle the breadcrumbs on top and drizzle with melted butter for added crunch.

Bake

Preheat your oven to 350°F (175°C). Bake the casserole for 30-35 minutes or until the top is golden brown and bubbly.

Serve

Remove the casserole from the oven and let it cool for a few minutes before serving. Enjoy!.

This casserole is best served warm and makes for great leftovers!

Storage Tips

Leftover Southern Squash Casserole can be stored in an airtight container in the refrigerator for up to three days. To reheat, simply place it in the microwave or oven until warmed through. The flavors tend to deepen over time, which many find makes it even tastier on subsequent days.

If you prefer to make this dish ahead of time, consider assembling the casserole without baking it. Cover it tightly and refrigerate until you’re ready to cook. Just add an extra 10 minutes to the baking time if you're starting from cold.

Serving Suggestions

This casserole can be served as a hearty side dish or as a main course for a light meal. Pair it with a crisp garden salad to provide a refreshing contrast to the rich flavors of the casserole. A light vinaigrette can balance the creaminess beautifully.

For an elevated experience, top the casserole with fresh herbs like parsley or chives just before serving. This not only adds vibrant color but also enhances the aroma, making it even more inviting and appealing to your guests.

Questions About Recipes

→ Can I use frozen butternut squash?

Yes, just make sure to thaw and drain any excess moisture before using.

→ How can I make this dish gluten-free?

Substitute the regular breadcrumbs with gluten-free breadcrumbs.